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Senior Bioinformatician (RNA Structure)

Serna Bio

Serna Bio

Boston, MA, USA
Posted on Thursday, July 4, 2024

Senior Bioinformatician (RNA Structure)

Serna Bio is building the world’s first map of the druggable transcriptome, systematically opening up the universe of RNA biology to small molecule drug discovery. Using our Discovery Platform, we are tackling the classically intractable targets ranging from coding and non-coding RNA.

The Team You’ll Join

As a Senior bioinformatician at Serna Bio, you will be a key member of the computational biology team, working closely and cross-functionally with our biology, high throughput screening and engineering teams, primarily focussed on organizing data associated with RNA structure analysis.

Your work will inform and support our R&D projects and our therapeutic program progression. You’ll play a key role in the development of novel structure-based target ID work.

Key Responsibilities

  • Working closely with our CSO, Danny Incarnato, you’ll be building novel bioinformatics pipelines to progress our target ID platform which have a direct impact on our programs.
  • Taking ownership and managing our existing target ID platform and associated pipelines to enable identification of suitable regions in RNA to target.
  • Using RNA structure prediction to understand RNA structure-function relationships
  • Helping to develop computational pipelines for analyzing chemical probing experiments, such as SHAPE-MaP