About us

Serna Bio is pioneering the first comprehensive map of the druggable transcriptome, unlocking the vast potential of RNA biology for small-molecule drug discovery. Our innovative Discovery Platform addresses traditionally challenging targets across both coding and non-coding RNA.

We are seeking a skilled Assay Development Specialist to contribute to our early-stage drug discovery project timelines by leading experiment design.

The Impact You’ll Make

• Be our internal expert in assay development, directing high-content, cell-based, biochemical and biophysical assay development (SPR, etc) for multiple targets

The Team You’ll Join

We are looking for an Assay Development Specialist to work with us to advise on the design and execution of HTS screening assays.

Main Responsibilities:

• Act as an internal assay development specialist
• Design and development of small molecule high throughput screening assays
• Drive statistical analysis choices with the computational team
• Design and develop screening cascade for core programs in collaboration with drug discovery team
• Direct high-content, cell-based, biochemical and biophysical assay development for multiple targets
• Manage the transfer and implementation of assay cascades with CRO partners.
• Design reporter vectors and led cell-line engineering activities with CROs.
• Help implement data analysis workflows and develop business rules for dose-response curve QC, hit-calling and assay performance monitoring.